Exporting Hyperinflation: The Long Arm of Chiang Kai-shek

As mainland China's inflationary spiral accelerated in 1947-1949 there was a massive outflow of funds to the island of Taiwan. The exporting of China's hyperinflation was facilitated by the fixed, overvalued, exchange rate between the mainland Chinese currency and the Taiwanese currency that was adopted in August 1948. Empirical tests offer support for the importance of the 1948 monetary policy reform and suggest a substantial impact of capital inflows and excess money growth in mainland China on inflationary pressures in Taiwan. We find no independent role for Taiwanese money growth in the inflation process.

Contextual Utility and Practicality: Cultural Research for the School Community in Hong Kong

As an intellectual project, is cultural studies actually ‘useless’ in dealing with issues closely tied to students’ everyday practices? In this article, the authors examine the problem through the case of teacher training and curriculum development in the context of educational reform in Hong Kong—in particular, through a community-interface project we are engaged in as cultural researchers at the moment

Computer-mediated-communication and social networking tools at work

Purpose – Advances in information technology (IT) have resulted in the development of various computer‐mediated communication (CMC) and social networking tools. However, quantifying the benefits of utilizing these tools in the organizational context remains a challenge. In this study, the authors aim to investigate the effects of three specific tools, viz. instant messenger, email and knowledge forum, on facilitating the communication and social network at work, and their subsequent influence on individuals’ work performance. Together with a social network diagram, the proposed model is validated by a survey of 59 employees of a company which embeds these three CMC and social networking tools in the work process. The key findings, implications and future research are discussed. Design/methodology/approach – The authors verify the research model with data from the Hong Kong office of an international bank headquartered in London, UK. They also collected the data on the social networks of 59 employees to draw a network diagram of the respondents using the social network analysis software UCINET. Findings – The research model is fully supported by the survey data. Meanwhile, the social networks analysis also suggests the linkage of using IM at work and the high level of degree and high level of closeness. Originality/value – This study provided an empirical verification of media performance theories, evidenced by interactive tools such as IM and email. This research also directly linked the elements of social network, viz. degree, closeness and betweenness, with the CMC and social network tools, the communication, interactivity, relationship, and work performance

Grouping-Enabled and Privacy-Enhancing Communications Schemes for VANETs

Open Access Bookpublished_or_final_versio

Cloud Forensics Investigation: Tracing Infringing Sharing of Copyrighted Content in Cloud

Cloud Computing is becoming a significant technology trend nowadays, but its abrupt rise also creates a brand new front for cybercrime investigation with various challenges. One of the challenges is to track down infringing sharing of copyrighted content in cloud. To solve this problem, we study a typical type of content sharing technologies in cloud computing, analyze the challenges that the new technologies bring to forensics, formalize a procedure to get digital evidences and obtain analytical results based on the evidences to track down illegal uploader. Furthermore, we propose a reasoning model based on the probability distribution in a Bayesian Network to evaluate the analytical result of forensics examinations. The proposed method can accurately and scientifically track down the origin infringing content uploader and owner. Keywords: cloud forensics, peer to peer, file sharing, tracking, CloudFron

Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways

10.1371/journal.pone.0032476PLoS ONE73

Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions

BACKGROUND: Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the relationship of NSS to other neuropsychological performances. METHODS: Twenty-nine people with aMCI and 28 cognitively healthy elderly people were recruited for the present study. The NSS subscales (motor coordination, sensory integration, and disinhibition) of the Cambridge Neurological Inventory and a set of neuropsychological tests were administered to all the participants. RESULTS: People with aMCI exhibited significantly more motor coordination signs, disinhibition signs, and total NSS than normal controls. Correlation analysis showed that the motor coordination subscale score and total score of NSS were significantly inversely correlated with the combined Z-score of neuropsychological tests in aMCI group. CONCLUSIONS: These preliminary findings suggested that people with aMCI demonstrated a higher prevalence of NSS compared to healthy elderly people. Moreover, NSS was found to be inversely correlated with the neuropsychological performances in persons with aMCI. When taken together, these findings suggested that NSS may play a potential important role and serve as a tool to assist in the early detection of aMCI

Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro

The mechanism by which TGF-β regulates renal inflammation and fibrosis is largely unclear; however, it is well accepted that its biological effects are mediated through Smad2 and Smad3 phosphorylation. Following activation, these Smads form heteromeric complex with Smad4 and translocate into the nucleus to bind and regulate the expression of target genes. Here we studied the roles of Smad4 to regulate TGF-β signaling in a mouse model of unilateral ureteral obstruction using conditional Smad4 knockout mice and in isolated Smad4 mutant macrophages and fibroblasts. Disruption of Smad4 significantly enhanced renal inflammation as evidenced by a greater CD45+ leukocyte and F4/80+ macrophage infiltration and upregulation of IL-1β, TNF-α, MCP-1, and ICAM-1 in the obstructed kidney and in IL-1β-stimulated macrophages. In contrast, deletion of Smad4 inhibited renal fibrosis and TGF-β1-induced collagen I expression by fibroblasts. Further studies showed that the loss of Smad4 repressed Smad7 transcription, leading to a loss of functional protein. This, in turn, inhibited IκBα expression but enhanced NF-κB activation, thereby promoting renal inflammation. Interestingly, deletion of Smad4 influenced Smad3-mediated promoter activities and the binding of Smad3 to the COL1A2 promoter, but not Smad3 phosphorylation and nuclear translocation, thereby inhibiting the fibrotic response. Thus, Smad4 may be a key regulator for the diverse roles of TGF-β1 in inflammation and fibrogenesis by interacting with Smad7 and Smad3 to influence their transcriptional activities in renal inflammation and fibrosis

Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog

10.1016/j.stem.2013.04.023Cell Stem Cell125531-54

Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3b

We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC-2020 March 27 17:00 UTC). We conduct two independent searches: A generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate. © 2022. The Author(s). Published by the American Astronomical Society